{"id":10875,"date":"2024-11-21T16:54:24","date_gmt":"2024-11-21T15:54:24","guid":{"rendered":"https:\/\/www.astrodose.eu\/?p=10875"},"modified":"2024-11-21T16:54:25","modified_gmt":"2024-11-21T15:54:25","slug":"mikrodavkovani-psilocybinu-muze-bojovat-proti-borelioze-po-lecbe","status":"publish","type":"post","link":"https:\/\/www.astrodose.eu\/cs\/science-and-studies\/microdosing-psilocybin-may-combat-post-treatment-lyme-disease\/","title":{"rendered":"Mikrod\u00e1vkov\u00e1n\u00ed psilocybinu m\u016f\u017ee bojovat s boreli\u00f3zou po l\u00e9\u010db\u011b"},"content":{"rendered":"<p class=\"wp-block-paragraph\" style=\"font-size:21px\"><strong>Lymsk\u00e1 boreli\u00f3za je infekce zp\u016fsoben\u00e1 kousnut\u00edm kl\u00ed\u0161t\u011btem. Pokud se nel\u00e9\u010d\u00ed, m\u016f\u017ee vy\u00fastit ve vy\u010derp\u00e1vaj\u00edc\u00ed chronick\u00e9 onemocn\u011bn\u00ed, kter\u00e9 m\u00e1 jen m\u00e1lo \u00fa\u010dinn\u00fdch mo\u017enost\u00ed l\u00e9\u010dby. V\u011bdci nyn\u00ed navrhuj\u00ed, aby se mikrod\u00e1vkov\u00e1n\u00ed psilocybinu <em>(psychoaktivn\u00ed l\u00e1tka v magick\u00fdch houb\u00e1ch).<\/em> by mohla p\u0159in\u00e9st \u00falevu.\u00a0<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kl\u00ed\u0161\u0165ata \u010dernohlav\u00e1\u00a0<em>(kl\u00ed\u0161\u0165ata jelen\u016f)\u00a0<\/em>\u017e\u00edt po cel\u00e9m sv\u011bt\u011b. To znamen\u00e1, \u017ee boreli\u00f3zou m\u016f\u017ee onemocn\u011bt kdokoli, zejm\u00e9na ti, kte\u0159\u00ed tr\u00e1v\u00ed hodn\u011b \u010dasu venku. Zat\u00edmco v\u011bt\u0161ina lid\u00ed, kte\u0159\u00ed se nakaz\u00ed boreli\u00f3zou, se uzdrav\u00ed, pro n\u011bkter\u00e9 se m\u016f\u017ee st\u00e1t vy\u010derp\u00e1vaj\u00edc\u00edm stavem, kter\u00fd m\u016f\u017ee naru\u0161it jejich fyzickou, du\u0161evn\u00ed a emocion\u00e1ln\u00ed pohodu.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-what-is-lyme-disease\">Co je to boreli\u00f3za?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Lymsk\u00e1 boreli\u00f3za je infekce zp\u016fsoben\u00e1 kousnut\u00edm kl\u00ed\u0161\u0165at, kter\u00e1 jsou sama infikov\u00e1na bakteri\u00ed.\u00a0<em>Borrelia burgdorferi.\u00a0<\/em>V roce 2022\u00a0<em>BMJ Global Health\u00a0<\/em>\u010dasopis zve\u0159ejnil\u00a0<a href=\"https:\/\/gh.bmj.com\/content\/7\/6\/e007744.info\" target=\"_blank\" rel=\"noreferrer noopener\">studium<\/a>\u00a0kter\u00e1 odhaduje, \u017ee 14.5% sv\u011btov\u00e9 populace bylo n\u011bkdy infikov\u00e1no boreli\u00f3zou. Toto \u010d\u00edslo se bude d\u00e1le zvy\u0161ovat, proto\u017ee po\u010det diagnostikovan\u00fdch p\u0159\u00edpad\u016f boreli\u00f3zy se v posledn\u00edm desetilet\u00ed ji\u017e zdvojn\u00e1sobil v d\u016fsledku klimatick\u00fdch zm\u011bn, kter\u00e9 zp\u016fsobuj\u00ed del\u0161\u00ed jaro a vy\u0161\u0161\u00ed teploty.\u00a0<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"640\" height=\"325\" src=\"https:\/\/www.astrodose.eu\/wp-content\/uploads\/deer-tick-on-a-leaf.jpg\" alt=\"\" class=\"wp-image-10876\" style=\"width:840px;height:auto\" srcset=\"https:\/\/www.astrodose.eu\/wp-content\/uploads\/deer-tick-on-a-leaf.jpg 640w, https:\/\/www.astrodose.eu\/wp-content\/uploads\/deer-tick-on-a-leaf-300x152.jpg 300w, https:\/\/www.astrodose.eu\/wp-content\/uploads\/deer-tick-on-a-leaf-18x9.jpg 18w, https:\/\/www.astrodose.eu\/wp-content\/uploads\/deer-tick-on-a-leaf-600x305.jpg 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><figcaption class=\"wp-element-caption\"><em><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-cyan-bluish-gray-color\">Foto: Erik Karits<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-what-are-the-symptoms-of-lyme-disease\">Jak\u00e9 jsou p\u0159\u00edznaky boreli\u00f3zy?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">P\u0159\u00edznaky&nbsp;<em>(neo\u0161et\u0159en\u00e9)<\/em>&nbsp;Lymsk\u00e1 boreli\u00f3za se li\u0161\u00ed podle toho, v jak\u00e9 f\u00e1zi se infekce nach\u00e1z\u00ed.&nbsp;<\/p>\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-stage-1-early-localized-stage-1-4-weeks-after-infection\">F\u00e1ze 1&nbsp;<em>(\u010dasn\u00e9 lokalizovan\u00e9 stadium\/ 1-4 t\u00fddny po infekci)<\/em><\/h5>\n\n\n\n<ul class=\"wp-block-list\">\n<li>V\u00fdrazn\u00e1 vyr\u00e1\u017eka \"b\u00fd\u010d\u00ed oko\", kter\u00e1 se roz\u0161i\u0159uje sm\u011brem ven z m\u00edsta kousnut\u00ed kl\u00ed\u0161t\u011btem.<\/li>\n\n\n\n<li>P\u0159\u00edznaky podobn\u00e9 ch\u0159ipce, jako je hore\u010dka, \u00fanava, bolesti sval\u016f a kloub\u016f, bolest hlavy, ztuhl\u00fd krk a zdu\u0159en\u00ed lymfatick\u00fdch uzlin.\u00a0<\/li>\n<\/ul>\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-stage-2-early-disseminated-stage-1-4-months-after-infection\">F\u00e1ze 2&nbsp;<em>(\u010dasn\u00e9 diseminovan\u00e9 stadium\/ 1-4 m\u011bs\u00edce po infekci)<\/em><\/h5>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Neurologick\u00e9 p\u0159\u00edznaky, jako je necitlivost, brn\u011bn\u00ed kon\u010detin a pokles obli\u010deje v d\u016fsledku ochrnut\u00ed.\u00a0<em>(Bellova obrna).<\/em><\/li>\n\n\n\n<li>Vyr\u00e1\u017eky v r\u016fzn\u00fdch oblastech t\u011bla<\/li>\n\n\n\n<li>Bu\u0161en\u00ed srdce v d\u016fsledku z\u00e1n\u011btu<\/li>\n\n\n\n<li>Z\u00e1vrat\u011b<\/li>\n\n\n\n<li>Du\u0161nost<\/li>\n<\/ul>\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-stage-3-late-disseminated-stage-4-months-post-infection\">F\u00e1ze 3&nbsp;<em>(pozdn\u00ed diseminovan\u00e9 stadium\/ 4 m\u011bs\u00edce a v\u00edce po infekci)<\/em><\/h5>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dlouhodob\u011b nel\u00e9\u010den\u00e1 boreli\u00f3za m\u016f\u017ee v\u00e9st k \"boreliov\u00e9 artritid\u011b\", p\u0159etrv\u00e1vaj\u00edc\u00edmu z\u00e1n\u011btu kloub\u016f, zejm\u00e9na v\u011bt\u0161\u00edch kloub\u016f, jako jsou kolena.\u00a0<\/li>\n\n\n\n<li>Bolest, otok a ztuhlost kloub\u016f<\/li>\n\n\n\n<li>Ztr\u00e1ta pam\u011bti, kognitivn\u00ed probl\u00e9my a pot\u00ed\u017ee se soust\u0159ed\u011bn\u00edm\u00a0<em>(Encefalopatie)<\/em><\/li>\n\n\n\n<li>Brn\u011bn\u00ed, bolest nebo necitlivost kon\u010detin.\u00a0<em>(kon\u010detiny)<\/em><\/li>\n\n\n\n<li>Poruchy sp\u00e1nku<\/li>\n\n\n\n<li>zm\u011bny n\u00e1lady, jako je deprese nebo \u00fazkost.\u00a0<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-how-is-lyme-disease-diagnosed\">Jak se diagnostikuje boreli\u00f3za?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Pokud nen\u00ed kousnut\u00ed kl\u00ed\u0161t\u011btem zachyceno v\u010das, proto\u017ee kl\u00ed\u0161t\u011b je st\u00e1le p\u0159\u00edtomno, nebo pokud nen\u00ed viditeln\u00e1 charakteristick\u00e1 vyr\u00e1\u017eka ve tvaru b\u00fd\u010d\u00edho oka, m\u016f\u017ee b\u00fdt obt\u00ed\u017en\u00e9 diagnostikovat boreli\u00f3zu, proto\u017ee jej\u00ed p\u0159\u00edznaky napodobuj\u00ed mnoho jin\u00fdch stav\u016f. L\u00e9ka\u0159 posoud\u00ed pravd\u011bpodobnost boreli\u00f3zy na z\u00e1klad\u011b kombinace n\u011bkolika faktor\u016f a pot\u00e9 se obvykle provede krevn\u00ed test, kter\u00fd odhal\u00ed protil\u00e1tky a potvrd\u00ed diagn\u00f3zu.&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" width=\"433\" height=\"262\" src=\"https:\/\/www.astrodose.eu\/wp-content\/uploads\/bulls-eye-rash-lyme.jpg\" alt=\"\" class=\"wp-image-10877\" style=\"width:840px;height:auto\" srcset=\"https:\/\/www.astrodose.eu\/wp-content\/uploads\/bulls-eye-rash-lyme.jpg 433w, https:\/\/www.astrodose.eu\/wp-content\/uploads\/bulls-eye-rash-lyme-300x182.jpg 300w, https:\/\/www.astrodose.eu\/wp-content\/uploads\/bulls-eye-rash-lyme-18x12.jpg 18w\" sizes=\"(max-width: 433px) 100vw, 433px\" \/><figcaption class=\"wp-element-caption\"><em><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-cyan-bluish-gray-color\">Vyr\u00e1\u017eka charakteristick\u00e1 pro boreli\u00f3zu (p\u0159es Wikimedia Commons)<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-treatment-options-for-lyme-disease\">Mo\u017enosti l\u00e9\u010dby boreli\u00f3zy<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u010casn\u00e9 stadium boreli\u00f3zy se \u00fa\u010dinn\u011b l\u00e9\u010d\u00ed 10-14denn\u00edm pod\u00e1v\u00e1n\u00edm antibiotik p\u0159edepsan\u00fdch l\u00e9ka\u0159em.\u00a0<\/li>\n\n\n\n<li>U jedinc\u016f se z\u00e1va\u017en\u00fdmi p\u0159\u00edznaky, kter\u00e9 postihuj\u00ed srdce nebo nervov\u00fd syst\u00e9m, m\u016f\u017ee b\u00fdt zapot\u0159eb\u00ed intraven\u00f3zn\u00ed pod\u00e1n\u00ed antibiotik.\u00a0<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-post-treatment-lyme-disease\">Lymsk\u00e1 boreli\u00f3za po l\u00e9\u010db\u011b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">V\u011bt\u0161ina lid\u00ed se po l\u00e9\u010db\u011b boreli\u00f3zy zotav\u00ed, n\u011bkte\u0159\u00ed jedinci v\u0161ak mohou trp\u011bt p\u0159etrv\u00e1vaj\u00edc\u00edmi p\u0159\u00edznaky zn\u00e1m\u00fdmi jako boreli\u00f3za po l\u00e9\u010db\u011b.&nbsp;<em>(PTLD)<\/em>. PTLD se obvykle diagnostikuje, pokud pacient pokra\u010duje v z\u00e1va\u017en\u00fdch p\u0159\u00edznac\u00edch po dobu 6 m\u011bs\u00edc\u016f nebo d\u00e9le po standardn\u00ed l\u00e9\u010db\u011b antibiotiky.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-post-treatment-lyme-disease-symptoms-include\">P\u0159\u00edznaky po l\u00e9\u010db\u011b boreli\u00f3zy zahrnuj\u00ed:<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Bolesti sval\u016f a kloub\u016f<\/li>\n\n\n\n<li>Kognitivn\u00ed poruchy\u00a0<\/li>\n\n\n\n<li>\u00danava<\/li>\n\n\n\n<li>Chronick\u00e9 bolesti hlavy<\/li>\n\n\n\n<li>Probl\u00e9my se sp\u00e1nkem<\/li>\n\n\n\n<li>Deprese<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Pro\u010d se u n\u011bkter\u00fdch lid\u00ed PTLD vyvine, nen\u00ed jasn\u00e9, ale v\u011bdci se domn\u00edvaj\u00ed, \u017ee by to mohlo b\u00fdt zp\u016fsobeno zm\u011bnami imunitn\u00edho syst\u00e9mu zp\u016fsoben\u00fdmi infekc\u00ed nebo dlouhodob\u00fdm z\u00e1n\u011btem. L\u00e9\u010dba tohoto onemocn\u011bn\u00ed se obecn\u011b zam\u011b\u0159uje na l\u00e9\u010dbu p\u0159\u00edznak\u016f, proto\u017ee antibiotika nezab\u00edraj\u00ed. To znamen\u00e1, \u017ee kvalita \u017eivota lid\u00ed, kte\u0159\u00ed \u017eij\u00ed s boreli\u00f3zou po l\u00e9\u010db\u011b, je \u010dasto siln\u011b naru\u0161ena.&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image is-resized\"><img decoding=\"async\" src=\"https:\/\/bunny-wp-pullzone-bor9ygkeip.b-cdn.net\/wp-content\/uploads\/diagnostic-test.jpg\" alt=\"\" class=\"wp-image-215930\" style=\"width:840px;height:auto\"\/><figcaption class=\"wp-element-caption\"><em><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-cyan-bluish-gray-color\">Foto: Marino Linic on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-could-psilocybin-help-those-with-lyme-disease\">Mikrod\u00e1vkov\u00e1n\u00ed psilocybinu m\u016f\u017ee bojovat s boreli\u00f3zou po l\u00e9\u010db\u011b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Psilocybin,\u00a0<em>(psychedelick\u00e1 slou\u010denina v magick\u00fdch houb\u00e1ch a lan\u00fd\u017e\u00edch).\u00a0<\/em>se uk\u00e1zala jako \u00fa\u010dinn\u00e1 p\u0159i l\u00e9\u010db\u011b du\u0161evn\u00edch poruch, v\u010detn\u011b.\u00a0<a href=\"https:\/\/www.astrodose.eu\/cs\/vyhody\/uzivani-kouzelnych-lanyzu-proti-depresi\/\" target=\"_blank\" rel=\"noreferrer noopener\">deprese<\/a>, PTSD, <a href=\"https:\/\/www.astrodose.eu\/cs\/vyhody\/mikrodavkovani-pri-socialni-uzkosti\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u00fazkost<\/a>,\u00a0<a href=\"https:\/\/www.astrodose.eu\/cs\/vyhody\/mikrodavkovani-pri-zavislosti-na-nikotinu\/\" target=\"_blank\" rel=\"noreferrer noopener\">probl\u00e9my se z\u00e1vislost\u00ed<\/a>a poruchy p\u0159\u00edjmu potravy. Krom\u011b toho se objevily zaj\u00edmav\u00e9 n\u00e1znaky, \u017ee by tato slou\u010denina mohla b\u00fdt pou\u017eita tak\u00e9 k l\u00e9\u010db\u011b chronick\u00fdch onemocn\u011bn\u00ed, jako jsou nap\u0159.\u00a0<a href=\"https:\/\/www.sciencealert.com\/one-patients-long-covid-improved-after-taking-hallucinogens-in-therapy\" target=\"_blank\" rel=\"noreferrer noopener\">Dlouh\u00fd COVID<\/a>\u00a0a\u00a0<a href=\"https:\/\/www.astrodose.eu\/cs\/vyhody\/uzivani-kouzelnych-lanyzu-proti-klastrovym-bolestem-hlavy\/\" target=\"_blank\" rel=\"noreferrer noopener\">klastrov\u00e9 bolesti hlavy<\/a>. V\u011bdci se nyn\u00ed domn\u00edvaj\u00ed, \u017ee psilocybin m\u016f\u017ee m\u00edt potenci\u00e1l i pro l\u00e9\u010dbu boreli\u00f3zy po l\u00e9\u010db\u011b.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">P\u0159esto\u017ee v\u00fdzkum \u00fa\u010dink\u016f psilocybinu na PTLD je zat\u00edm omezen\u00fd, na z\u00e1klad\u011b zn\u00e1m\u00fdch mechanism\u016f psilocybinu&nbsp;<em>(zejm\u00e9na jeho serotonergn\u00ed a protiz\u00e1n\u011btliv\u00e9 \u00fa\u010dinky).<\/em>, lze p\u0159edpokl\u00e1dat, \u017ee by mohl zm\u00edrnit p\u0159\u00edznaky spojen\u00e9 s t\u00edmto stavem.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-how-would-psilocybin-help-with-ptld-nbsp\">Jak by mikrod\u00e1vkov\u00e1n\u00ed psilocybinu pomohlo p\u0159i PTLD?\u00a0<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Psilocybin p\u016fsob\u00ed p\u0159edev\u0161\u00edm aktivac\u00ed serotoninov\u00fdch receptor\u016f, zejm\u00e9na receptoru 5-HT2A, kter\u00fd hraje kl\u00ed\u010dovou roli v regulaci n\u00e1lady a kognitivn\u00edch funkc\u00ed. Tento mechanismus nab\u00edz\u00ed n\u011bkolik potenci\u00e1ln\u00edch v\u00fdhod pro PTLD:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Podle\u00a0<strong>stimulace serotoninov\u00fdch receptor\u016f v mozku.<\/strong>, psilocybin m\u016f\u017ee\u00a0<strong>zlep\u0161it n\u00e1ladu\u00a0<\/strong>t\u00edm se sni\u017euje deprese a \u00fazkost.\u00a0<em>(\u010dast\u00e9 u pacient\u016f s PTLD).<\/em><\/li>\n\n\n\n<li>Psilocybin m\u016f\u017ee<strong>\u00a0pomoc p\u0159i regulaci emoc\u00ed<\/strong>\u00a0proto\u017ee podporuje neuroplasticitu a pom\u00e1h\u00e1 mozku vytv\u00e1\u0159et nov\u00e1 spojen\u00ed.\u00a0<\/li>\n\n\n\n<li>Pos\u00edlen\u00ed neuroplasticity a neurogeneze spojen\u00e9 s psilocybinem m\u016f\u017ee\u00a0<strong>zlep\u0161uj\u00ed pam\u011b\u0165, soust\u0159ed\u011bn\u00ed a celkovou kognitivn\u00ed flexibilitu.\u00a0\u00a0<\/strong><\/li>\n\n\n\n<li>Psilocybin by mohl\u00a0<strong>zm\u00edrnit chronick\u00fd z\u00e1n\u011bt<\/strong>\u00a0\u010dasto se vyskytuje u PTLD,\u00a0<strong>reduk\u010dn\u00ed kloub<\/strong>\u00a0a\u00a0<strong>bolesti sval\u016f<\/strong>.\u00a0<\/li>\n\n\n\n<li>Podobn\u011b v\u00fdzkum ukazuje, \u017ee psilocybin m\u016f\u017ee\u00a0<strong>sn\u00ed\u017eit hladinu proz\u00e1n\u011btliv\u00fdch cytokin\u016f.<\/strong>\u00a0jako jsou TNF-\u03b1 a IL-6, kter\u00e9 se pod\u00edlej\u00ed na imunitn\u00ed reakci organismu. Sn\u00ed\u017een\u00ed t\u011bchto cytokin\u016f m\u016f\u017ee tak\u00e9 pomoci\u00a0<strong>zm\u00edrnit chronick\u00fd z\u00e1n\u011bt<\/strong>\u00a0kter\u00e1 p\u0159isp\u00edv\u00e1 k p\u0159\u00edznak\u016fm PTLD, jako jsou bolesti kloub\u016f a \u00fanava.\u00a0<\/li>\n\n\n\n<li>Pacienti s PTLD \u010dasto trp\u00ed chronickou bolest\u00ed. Vzhledem k tomu, \u017ee serotonin moduluje bolest, mohl by \u00fa\u010dinek psilocybinu na serotonergn\u00ed dr\u00e1hy\u00a0<strong>sn\u00ed\u017eit chronickou bolest.<\/strong><\/li>\n\n\n\n<li>\u00da\u010dinek psilocybinu na nervov\u00e9 obvody m\u016f\u017ee b\u00fdt\u00a0<strong>m\u011bn\u00ed zp\u016fsob, jak\u00fdm mozek zpracov\u00e1v\u00e1 bolest.<\/strong>, tedy potenci\u00e1ln\u011b\u00a0<strong>zm\u00edrn\u011bn\u00ed chronick\u00e9 bolesti.<\/strong><\/li>\n\n\n\n<li>Bylo prok\u00e1z\u00e1no, \u017ee psilocybin pom\u00e1h\u00e1 lidem, kte\u0159\u00ed \u017eij\u00ed s chorobami m\u011bn\u00edc\u00edmi \u017eivot, a tak\u00e9 zm\u00edr\u0148uje \u00fazkost ze smrti u nevyl\u00e9\u010diteln\u011b nemocn\u00fdch pacient\u016f. T\u011bm, kte\u0159\u00ed trp\u00ed PTLD, m\u016f\u017ee pomoci p\u0159i\u00a0<strong>p\u0159er\u00e1mcov\u00e1n\u00ed jejich zku\u0161enost\u00ed.\u00a0<\/strong><\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" width=\"591\" height=\"285\" src=\"https:\/\/www.astrodose.eu\/wp-content\/uploads\/magic-truffle-microdose-methods-8.png\" alt=\"\" class=\"wp-image-10878\" style=\"width:840px;height:auto\" srcset=\"https:\/\/www.astrodose.eu\/wp-content\/uploads\/magic-truffle-microdose-methods-8.png 591w, https:\/\/www.astrodose.eu\/wp-content\/uploads\/magic-truffle-microdose-methods-8-300x145.png 300w, https:\/\/www.astrodose.eu\/wp-content\/uploads\/magic-truffle-microdose-methods-8-18x9.png 18w\" sizes=\"(max-width: 591px) 100vw, 591px\" \/><figcaption class=\"wp-element-caption\"><em><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-cyan-bluish-gray-color\">Mohou psilocybinov\u00e9 lan\u00fd\u017ee l\u00e9\u010dit boreli\u00f3zu po l\u00e9\u010db\u011b?<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>M\u016f\u017ee mikrod\u00e1vkov\u00e1n\u00ed psilocybinu l\u00e9\u010dit boreli\u00f3zu? P\u0159\u00edpadov\u00e1 studie<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A 2023&nbsp;<a href=\"https:\/\/www.dovepress.com\/the-effectiveness-of-microdosed-psilocybin-in-the-treatment-of-neurops-peer-reviewed-fulltext-article-IMCRJ\" target=\"_blank\" rel=\"noreferrer noopener\">p\u0159\u00edpadov\u00e1 studie<\/a>&nbsp;70let\u00e9ho mu\u017ee s boreli\u00f3zou po l\u00e9\u010db\u011b byla prvn\u00ed sv\u00e9ho druhu, kter\u00e1 sledovala \u00fa\u010dinek psilocybinu na tento stav.&nbsp;<\/p>\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-the-case-study\">P\u0159\u00edpadov\u00e1 studie:<\/h5>\n\n\n\n<ul class=\"wp-block-list\">\n<li>P\u0159\u00edpadov\u00e1 studie se skl\u00e1dala z\u00a0<strong>70let\u00fd mu\u017e, kter\u00fd byl pozitivn\u011b testov\u00e1n na boreli\u00f3zu.<\/strong>\u00a0ve v\u011bku 46 let pot\u00e9, co za\u017eil<em>\u00a0\"hore\u010dka, ztuhlost, mokvaj\u00edc\u00ed pot a myalgie\".<\/em>. Byl l\u00e9\u010den antibiotiky peror\u00e1ln\u00edmi doxycyklinem, klaritromycinem nebo cefuroximem, nicm\u00e9n\u011b.\u00a0<strong>jeho p\u0159\u00edznaky nezmizely<\/strong>a nakonec\u00a0<strong>ukon\u010dil l\u00e9\u010dbu antibiotiky.<\/strong>\u00a0<\/li>\n\n\n\n<li>B\u011bhem n\u00e1sleduj\u00edc\u00edch 20 let prod\u011bl\u00e1v\u00e1 \u010d\u00e1ste\u010dn\u00e9 remise i recidivy. Krom\u011b p\u0159edchoz\u00edch p\u0159\u00edznak\u016f se u n\u011bj objevily tak\u00e9\u00a0<strong>deprese<\/strong>,<strong>\u00a0\u00fazkost,<\/strong>\u00a0<strong>z\u00e1chvaty paniky<\/strong>,\u00a0<strong>kognitivn\u00ed dysfunkce<\/strong>,\u00a0<strong>nespavost<\/strong>\u00a0a\u00a0<strong>\u00fanava<\/strong>. Byla mu p\u0159edeps\u00e1na antidepresiva, ale jejich \u00fa\u010dinky byly nesnesiteln\u00e9, a tak je p\u0159estal u\u017e\u00edvat.\u00a0<\/li>\n\n\n\n<li>V 70 letech, po zm\u011bn\u011b antimikrobi\u00e1ln\u00ed rutiny, m\u011bl\u00a0<strong>recidiva<\/strong>. Trp\u011bl fyzick\u00fdmi i psychick\u00fdmi p\u0159\u00edznaky a jak\u00e1koli antimikrobi\u00e1ln\u00ed l\u00e9\u010dba nebo l\u00e9ky proti \u00fazkosti jeho p\u0159\u00edznaky je\u0161t\u011b zhor\u0161ovaly.\u00a0<\/li>\n\n\n\n<li>Po 3 m\u011bs\u00edc\u00edch bez \u00falevy\u00a0<strong>za\u010dal mikrod\u00e1vkovat su\u0161en\u00e9 magick\u00e9 houby.<\/strong><em><strong>\u00a0<\/strong>(100 mg t\u0159ikr\u00e1t t\u00fddn\u011b a po dvou t\u00fddnech 125 mg).\u00a0<\/em><\/li>\n\n\n\n<li>Mu\u017e uvedl, \u017ee\u00a0<strong>jeho n\u00e1lada se zlep\u0161ila b\u011bhem 2 dn\u016f<\/strong>. C\u00edtil se\u00a0<strong>trvale dob\u0159e po dvou t\u00fddnech<\/strong>. O dva roky pozd\u011bji a st\u00e1le pokra\u010duje v tomto re\u017eimu,\u00a0<strong>jeho deprese a \u00fazkosti jsou st\u00e1le v remisi.\u00a0<\/strong><\/li>\n\n\n\n<li>Pacient uvedl, \u017ee kdy\u017e za\u010dal s mikrod\u00e1vkov\u00e1n\u00edm, o\u010dek\u00e1val, \u017ee bude trvat nejm\u00e9n\u011b dva t\u00fddny, ne\u017e se projev\u00ed n\u011bjak\u00e9 \u00fa\u010dinky, pokud v\u016fbec. Proto byl\u00a0<strong>up\u0159\u00edmn\u011b p\u0159ekvapen \u00fa\u010dinnost\u00ed psilocybinu<\/strong>, kdy\u017e se v\u00fdsledky objevily tak rychle.\u00a0<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/bunny-wp-pullzone-bor9ygkeip.b-cdn.net\/wp-content\/uploads\/astrodose-microdosing-psilocybin-strip-21.png\" alt=\"\" class=\"wp-image-215933\"\/><figcaption class=\"wp-element-caption\"><em><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-cyan-bluish-gray-color\">mikrod\u00e1vkov\u00fd prou\u017eek psilocybinu<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Tato p\u0159\u00edpadov\u00e1 studie ukazuje zaj\u00edmav\u00fd potenci\u00e1l. V\u011bdci v\u0161ak upozor\u0148uj\u00ed, \u017ee k prozkoum\u00e1n\u00ed terapeutick\u00e9ho potenci\u00e1lu psilocybinu u boreli\u00f3zy po l\u00e9\u010db\u011b je t\u0159eba prov\u00e9st dal\u0161\u00ed studie. V sou\u010dasn\u00e9 dob\u011b prob\u00edh\u00e1 na Johns Hopkins Univeristy klinick\u00e1 studie.&nbsp;<em>&nbsp;\"zkoumat \u00fa\u010dinky psilocybinu na symptomy boreli\u00f3zy a kvalitu \u017eivota u lid\u00ed s boreli\u00f3zou po l\u00e9\u010db\u011b (PTLD).\"&nbsp;<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Lymsk\u00e1 boreli\u00f3za m\u016f\u017ee b\u00fdt chronick\u00fdm a vy\u010derp\u00e1vaj\u00edc\u00edm onemocn\u011bn\u00edm. To, \u017ee psilocybin m\u016f\u017ee potenci\u00e1ln\u011b zm\u00edrnit p\u0159\u00edznaky u t\u011bch, kte\u0159\u00ed j\u00edm trp\u00ed, je jist\u011b sv\u011btlo na konci tunelu. Z\u016fsta\u0148te nalad\u011bni!<\/strong><\/p>","protected":false},"excerpt":{"rendered":"<p>Lyme disease is an infection caused by tick bites. If left untreated it can result in a debilitating chronic illness, with little in the way of effective treatment options. Now, researchers are proposing that microdosing psilocybin (the psychoactive compound in magic mushrooms) could provide relief.\u00a0 Black legged-ticks\u00a0(deer ticks)\u00a0live all over the world. This means that [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":10880,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-10875","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-and-studies"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Microdosing Psilocybin May Combat Post-Treatment Lyme Disease<\/title>\n<meta name=\"description\" content=\"A new case study shows that microdosing psilocybin may combat Post-Treatment Lyme disease, a debilitating, chronic condition.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.astrodose.eu\/cs\/veda-a-studium\/mikrodavkovani-psilocybinu-muze-bojovat-proti-borelioze-po-lecbe\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Microdosing Psilocybin May Combat Post-Treatment Lyme Disease\" \/>\n<meta property=\"og:description\" content=\"A new case study shows that microdosing psilocybin may combat Post-Treatment Lyme disease, a debilitating, chronic condition.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.astrodose.eu\/cs\/veda-a-studium\/mikrodavkovani-psilocybinu-muze-bojovat-proti-borelioze-po-lecbe\/\" \/>\n<meta property=\"og:site_name\" content=\"Astrodose - 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