{"id":10110,"date":"2024-05-07T15:40:59","date_gmt":"2024-05-07T13:40:59","guid":{"rendered":"https:\/\/www.astrodose.eu\/?p=10110"},"modified":"2024-05-07T15:40:59","modified_gmt":"2024-05-07T13:40:59","slug":"undersogelse-viser-at-mikrodosering-af-psilocybin-er-lige-sa-effektivt-som-traditionel-smertestillende-medicin","status":"publish","type":"post","link":"https:\/\/www.astrodose.eu\/da\/science-and-studies\/study-finds-microdosing-psilocybin-as-effective-as-traditional-pain-medication\/","title":{"rendered":"Unders\u00f8gelse viser, at mikrodosering af psilocybin er lige s\u00e5 effektivt som traditionel smertestillende medicin"},"content":{"rendered":"

En nylig unders\u00f8gelse har vist, at kroniske smerter kan lindres af mikrodoser af psilocybin, det psykoaktive stof, der findes i magiske svampe.\u00a0<\/strong><\/p>\n\n\n\n

P\u00e5 dette tidspunkt t\u00e6nker du m\u00e5ske - OK, hvad s\u00e5?\u00a0kan ikke\u00a0<\/em>psykedelisk behandling? Og det kan man godt undre sig over. Men hvor vildt det end lyder, s\u00e5 er det sandt. Der er\u00a0er<\/em>\u00a0et voksende forskningsomr\u00e5de, der viser<\/strong> disse tidligere mistroede stoffer kan v\u00e6re balsam for fysisk smerte, ud over deres mere omtalte rolle som behandling af psykologiske problemer<\/a>.\u00a0<\/strong><\/p>\n\n\n\n

Psykedeliske stoffer mere effektive end konventionel medicin<\/h2>\n\n\n\n

The\u00a0unders\u00f8gelse<\/a>, udgivet i august 2023, (i det alt for passende navn European Journal of Pain)\u00a0<\/em>fandt, at doser af klassiske psykedelika - s\u00e5som\u00a0psilocybin,<\/strong>\u00a0LSD<\/strong>,\u00a0Meskalin<\/strong>\u00a0og\u00a0DMT<\/strong>\u00a0- var effektive i behandlingen af kroniske smerter. I b\u00e5de makro- og\u00a0Mikrodoser<\/strong>\u00a0Disse stoffer viste sig at f\u00f8re til\u00a0bedre smertelindring<\/strong>\u00a0sammenlignet med konventionel medicin<\/strong>. Unders\u00f8gelsen bestod af 170 frivillige.\u00a0<\/p>\n\n\n\n

Artiklen opsummerede resultaterne;<\/p>\n\n\n\n

\"Deltagerne rapporterede, at fulde doser synes at opn\u00e5 bedre opfattede resultater i smertelindring end mikrodosering, mens mikrodoseringens effektivitet synes at kunne sammenlignes med konventionel medicin if\u00f8lge deltagerne i unders\u00f8gelsen.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Lindrer smerter i op til 3 dage eller mere<\/h4>\n\n\n\n

I unders\u00f8gelsen fokuserede forskerne p\u00e5 fem tilstande. Disse var gigt, migr\u00e6ne, fibromyalgi<\/a>, sp\u00e6ndingshovedpine og iskias<\/a>. <\/p>\n\n\n\n

I unders\u00f8gelsen var alle de andre tilstande med undtagelse af iskias (s\u00e5 4 ud af 5<\/strong>) <\/em>blev rapporteret at blive lindret af psykedelika. Dette var mest effektiv p\u00e5 doseringsdagen<\/strong>men ogs\u00e5 mellem 1 og 3 dage <\/strong>senere. Nogle f\u00e5 af de adspurgte rapporterede endda om smertelindring efter den tredje dag. <\/strong><\/p>\n\n\n\n

Psilocybin<\/strong> og LSD<\/strong> var de mest anvendte stoffer blandt deltagerne i unders\u00f8gelsen. <\/p>\n\n\n\n

Sp\u00f8rgsm\u00e5let om hvorfor <\/em>psykedelika var ikke effektive, eller i det mindste \"statistisk ikke-signifikant\" <\/em>om iskias blev ogs\u00e5 overvejet af forskerne. Det skrev de;<\/p>\n\n\n\n

 \"Dette resultat kan indikere, at disse stoffer kun er lovende for visse former for smertetilstande, formentlig dem, hvor de inflammatoriske og\/eller psykosomatiske komponenter spiller en mere fremtr\u00e6dende rolle.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"
Foto af CHUTTERSNAP p\u00e5 Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Kroniske smerter er et stort problem p\u00e5 verdensplan<\/h2>\n\n\n\n

Dette afspejler\u00a0Tidligere forskning<\/a>\u00a0og spekulationer om, at psykedelika kan fungere som effektive\u00a0anti-inflammatorisk<\/strong>. Faktisk gentager denne unders\u00f8gelse tidligere resultater fra forskere, der studerer virkningerne af psykedelika p\u00e5 kronisk smerte - en ...\u00a0meget lovende tegn<\/strong>! En hel del\u00a020% af verdens befolkning<\/strong>\u00a0lider af\u00a0kronisk smerte\u00a0<\/strong>af en eller anden slags. Det kunne v\u00e6re revolutionerende at finde nye m\u00e5der at behandle dette problem p\u00e5. Forfatterne erkendte dog nogle begr\u00e6nsninger i unders\u00f8gelsen. Den st\u00f8rste l\u00e5 i selve unders\u00f8gelsens design. Det bem\u00e6rkede forskerne;<\/p>\n\n\n\n

\"Det giver rent retrospektive selvvurderinger fra en selvvalgt pr\u00f8ve af personer, der selv administrerer psykedelika ... Dette design medf\u00f8rer risikoen for at opn\u00e5 partiske data, og generaliserbarheden af de producerede resultater er kun begr\u00e6nset. Det giver begr\u00e6nset information til at adskille den rolle, som forskellige mekanismer spiller for at opn\u00e5 disse opfattede analgetiske effekter.\"<\/strong><\/em><\/p>\n\n\n\n

Forfatterne bem\u00e6rkede ogs\u00e5, at det betyder, at der er behov for kontrollerede unders\u00f8gelser. Til det form\u00e5l skal der designes kliniske fors\u00f8g for at skubbe forskningen videre. <\/p>\n\n\n\n

\"\"
Foto af Road Trip with Raj p\u00e5 Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Forskningsprogram for mikrodosering<\/h2>\n\n\n\n

Denne unders\u00f8gelse var blevet iv\u00e6rksat af den kendte psykedeliske fortaler Amanda Feilding, grundl\u00e6gger og direkt\u00f8r for Beckley Foundation. Den kom efter etableringen af\u00a0Beckley\/Maastricht-programmet for psykedelisk forskning<\/a>. Sp\u00e6ndende nok er dette program dedikeret til at studere effekterne af mikrodosering<\/a> <\/strong>psykedelika p\u00e5 kognitive funktioner, hum\u00f8r og smerteh\u00e5ndtering.\u00a0<\/p>\n\n\n\n

Tidligere havde programmet gennemf\u00f8rt et placebokontrolleret klinisk fors\u00f8g. unders\u00f8gelse<\/a> af 24 raske frivillige. I denne unders\u00f8gelse fandt man ud af, at en dosis p\u00e5 20 mikrogram LSD kunne reducere smerteopfattelsen betydeligt sammenlignet med placebo under en 'Test med koldt tryk<\/a>'. Da unders\u00f8gelsen blev offentliggjort i 2020, sagde Feilding;<\/p>\n\n\n\n

\"De nuv\u00e6rende data tyder p\u00e5, at lave doser LSD kan udg\u00f8re en nyttig behandlingsmulighed for smertebehandling, der ikke kun er effektiv hos patienter, men ogs\u00e5 er blottet for de problematiske konsekvenser, der er forbundet med de nuv\u00e6rende grundpiller, s\u00e5som opioider ...<\/strong><\/em>\"<\/p>\n\n\n\n

\"Jeg er opmuntret af disse resultater, da jeg l\u00e6nge har troet, at LSD ikke kun kan \u00e6ndre smertefornemmelsen, men ogs\u00e5 vores subjektive forhold til den. Vi m\u00e5 forts\u00e6tte med at udforske dette med det form\u00e5l at tilbyde sikrere, ikke-vanedannende alternativer til smertebehandling og bringe mennesker med smerter et skridt n\u00e6rmere et lykkeligere, sundere og fuldt udfoldet liv.\"<\/strong><\/em><\/p>\n\n\n\n

Der er adskillige andre smertelindringsrelaterede fors\u00f8g, som for nylig er afsluttet, planlagt eller stadig i gang. MindMed er ogs\u00e5 i gang med at udforske LSD mod kroniske smerter. En nylig unders\u00f8gelse p\u00e5 Imperial College London viste, at ni ud af elleve kroniske smertepatienter rapporterede total eller i det mindste delvis smertelindring. (eller manglende evne til at f\u00f8le smerte) <\/em>n\u00e5r man selvmedicinerer med psykedeliske stoffer. <\/p>\n\n\n\n

Styrkelse af den psykedeliske sag<\/h2>\n\n\n\n

Derudover bliver psykedeliske stoffers smertelindrende potentiale ogs\u00e5 brugt til at styrke deres kampagne for legalisering og afkriminalisering. I Californiens fors\u00f8g p\u00e5 at afkriminalisere psykedeliske stoffer stod Joe Mackay, som havde v\u00e6ret f\u00f8rstehj\u00e6lper under 9\/11, for eksempel frem. Han havde lidt af PTSD og klyngehovedpine siden begivenheden, og da han blev pensioneret, besluttede han sig for at fors\u00f8ge at helbrede sig selv ved hj\u00e6lp af magiske svampe. Som fortaler for den psykedeliske sag skrev han;<\/p>\n\n\n\n

\"For f\u00f8rste gang i mange \u00e5r f\u00f8lte jeg mig h\u00e5befuld med hensyn til mit helbred. Jeg holdt op med at tage den cocktail af piller, jeg havde f\u00e5et ordineret, hvoraf mange havde skadelige bivirkninger og var vanedannende ... Psilocybin hjalp mig ogs\u00e5 med at komme tilbage i kontakt med mit tidligere, glade jeg - den Joe, som mine venner og familie ikke havde set siden 9\/11. Det er ikke en overdrivelse at sige, at psilocybin gav mig mit liv tilbage. Det har v\u00e6ret transformerende og givet mig mulighed for at f\u00f8le lykke og gl\u00e6de p\u00e5 en m\u00e5de, jeg aldrig troede, jeg ville g\u00f8re igen.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"
Foto af freestocks p\u00e5 Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Prioritering af b\u00e5de mental og fysisk sundhed<\/h2>\n\n\n\n

Mental sundhed er lige s\u00e5 vigtigt<\/a> som fysisk sundhed, men dette begreb er relativt nyt i den brede bevidsthed. Der er stadig dem, der anser fysiske lidelser for at v\u00e6re mere alvorlige eller v\u00e6rd at tage sig af. Det er heldigt, Dette er ved at \u00e6ndre sig<\/strong>. M\u00e5ske vil vi nu, hvor psykedeliske stoffer viser sig at v\u00e6re effektive i behandlingen af fysisk smerte s\u00e5vel som mental sundhed, se en endnu st\u00f8rre stigning i fortalervirksomhed til gavn for b\u00e5de fysisk og mental sundhed. Det ser ud til, at psykedeliske stoffer er Den dobbelte trussel, vi har ventet p\u00e5<\/strong>...<\/p>","protected":false},"excerpt":{"rendered":"

A recent survey has found that chronic pain can be alleviated by microdoses of psilocybin, the psychoactive compound found in magic mushrooms.\u00a0 At this point you may be thinking \u2014 OK, so what\u00a0can\u2019t\u00a0psychedelics treat? And you\u2019d be forgiven for wondering. But as wild as it sounds, it\u2019s true. There\u00a0is\u00a0a growing area of research that shows […]<\/p>\n","protected":false},"author":11,"featured_media":10114,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-10110","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-and-studies"],"yoast_head":"\nStudy Finds Microdosing Psilocybin as Effective as Traditional Pain Medication<\/title>\n<meta name=\"description\" content=\"It's growing in popularity for mental health, but now a study finds microdosing psilocybin as effective as traditional paint medication!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.astrodose.eu\/da\/videnskab-og-studier\/undersogelse-viser-at-mikrodosering-af-psilocybin-er-lige-sa-effektivt-som-traditionel-smertestillende-medicin\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study Finds Microdosing Psilocybin as Effective as Traditional Pain Medication\" \/>\n<meta property=\"og:description\" content=\"It's growing in popularity for mental health, but now a study finds microdosing psilocybin as effective as traditional paint medication!\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.astrodose.eu\/da\/videnskab-og-studier\/undersogelse-viser-at-mikrodosering-af-psilocybin-er-lige-sa-effektivt-som-traditionel-smertestillende-medicin\/\" \/>\n<meta property=\"og:site_name\" content=\"Astrodose - 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