{"id":10110,"date":"2024-05-07T15:40:59","date_gmt":"2024-05-07T13:40:59","guid":{"rendered":"https:\/\/www.astrodose.eu\/?p=10110"},"modified":"2024-05-07T15:40:59","modified_gmt":"2024-05-07T13:40:59","slug":"uuring-leiab-et-psilotsubiini-mikrodoosimine-on-sama-tohus-kui-traditsioonilised-valuvaigistid","status":"publish","type":"post","link":"https:\/\/www.astrodose.eu\/et\/science-and-studies\/study-finds-microdosing-psilocybin-as-effective-as-traditional-pain-medication\/","title":{"rendered":"Uuring leiab, et psilots\u00fcbiini mikrodoosimine on sama t\u00f5hus kui traditsiooniline valuravi"},"content":{"rendered":"

Hiljutine uuring n\u00e4itas, et kroonilist valu v\u00f5ib leevendada psiilots\u00fcbiini mikrodooside abil, mis on maagilistes seentes sisalduv ps\u00fchhoaktiivne \u00fchend.\u00a0<\/strong><\/p>\n\n\n\n

Siinkohal v\u00f5ite te m\u00f5elda - OK, mis siis, et mida\u00a0ei saa\u00a0<\/em>ps\u00fchhedeelsed ained ravivad? Ja teile v\u00f5ib andeks anda, kui te m\u00f5tlete. Aga nii metsikult kui see ka ei k\u00f5la, on see t\u00f5si. Seal\u00a0on<\/em>\u00a0kasvav uurimisvaldkond, mis n\u00e4itab<\/strong> need varem umbusaldatud ained v\u00f5ivad olla balsamiks f\u00fc\u00fcsilise valu puhul, lisaks nende rohkem reklaamitud rollile raviks ps\u00fchholoogilised probleemid<\/a>.\u00a0<\/strong><\/p>\n\n\n\n

Ps\u00fchhedeelsed ained t\u00f5husamad kui tavalised ravimid<\/h2>\n\n\n\n

The\u00a0uuring<\/a>, avaldatud augustis 2023, (ajakirjas European Journal of Pain, mille nimi on liiga tabav)\u00a0<\/em>leidsid, et klassikaliste ps\u00fchhedeelikumide annused - nagu n\u00e4iteks\u00a0psilots\u00fcbiin,<\/strong>\u00a0LSD<\/strong>,\u00a0meskaliin<\/strong>\u00a0ja\u00a0DMT<\/strong>\u00a0- olid t\u00f5husad kroonilise valu ravis. Nii makro- kui ka\u00a0mikrodoosid<\/strong>\u00a0leiti, et need ained p\u00f5hjustavad\u00a0parem valu leevendamine<\/strong>\u00a0v\u00f5rreldes tavap\u00e4raste ravimitega<\/strong>. Uuringus osales 170 vabatahtlikku.\u00a0<\/p>\n\n\n\n

Artiklis v\u00f5eti tulemused kokku;<\/p>\n\n\n\n

\"Osalejad teatasid, et t\u00e4isdoosid n\u00e4ivad saavutavat parema tajutava tulemuse valu leevendamisel kui mikrodoosid, samas kui mikrodooside t\u00f5husus n\u00e4ib uuringus osalejate s\u00f5nul olevat v\u00f5rreldav tavap\u00e4raste ravimite t\u00f5hususega.\".<\/strong><\/em><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Valu leevendamine kuni 3 p\u00e4eva v\u00f5i kauemgi<\/h4>\n\n\n\n

Uuringus keskendusid teadlased viiele tingimusele. Need olid artriit, migreen, fibrom\u00fcalgia<\/a>, pinget\u00fc\u00fcpi peavalu ja Isiatika<\/a>. <\/p>\n\n\n\n

Uuringus, v\u00e4lja arvatud ishiase puhul, olid k\u00f5ik teised seisundid (nii 4 punkti 5-st<\/strong>) <\/em>on teatatud, et ps\u00fchhedeelsed ained leevendavad. See oli k\u00f5ige efektiivsem annustamisp\u00e4eval<\/strong>, kuigi ka 1 kuni 3 p\u00e4eva <\/strong>hiljem. M\u00f5ned k\u00fcsitletavad teatasid isegi valu leevendamisest p\u00e4rast kolmandat p\u00e4eva. <\/strong><\/p>\n\n\n\n

Psilots\u00fcbiin<\/strong> ja LSD<\/strong> olid uuringus osalejate poolt k\u00f5ige sagedamini kasutatavad ravimid. <\/p>\n\n\n\n

K\u00fcsimus miks <\/em>ps\u00fchhedeelsed ained ei olnud t\u00f5husad v\u00f5i v\u00e4hemalt \"statistiliselt mitteoluline\" <\/em>isheemiat\u00f5ve kohta m\u00f5tisklesid ka teadlased. Nad kirjutasid;<\/p>\n\n\n\n

 \"See tulemus v\u00f5ib viidata sellele, et need ained on paljulubavad ainult teatud t\u00fc\u00fcpi valuhaiguste puhul, arvatavasti nende puhul, kus p\u00f5letikuline ja\/v\u00f5i ps\u00fchhosomaatiline komponent m\u00e4ngib suuremat rolli.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"
Foto: CHUTTERSNAP on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Krooniline valu on tohutu probleem kogu maailmas<\/h2>\n\n\n\n

See peegeldab\u00a0varasemad uuringud<\/a>\u00a0ja spekulatsioonid, et ps\u00fchhedeelsed ained v\u00f5ivad toimida t\u00f5husate\u00a0p\u00f5letikuvastane<\/strong>. Tegelikult kordab see uuring varasemate teadlaste tulemusi, kes uurisid ps\u00fchhedeelikumite m\u00f5ju kroonilisele valule - see on\u00a0v\u00e4ga paljulubav m\u00e4rk<\/strong>! Terviklik\u00a020% maailma elanikkonnast<\/strong>\u00a0kannatavad\u00a0krooniline valu\u00a0<\/strong>mingisugune. Uute v\u00f5imalike raviv\u00f5imaluste leidmine v\u00f5ib olla revolutsiooniline. Autorid tunnistasid siiski uuringu m\u00f5ningaid piiranguid. Suurim oli uuringu \u00fclesehitus ise. Teadlased m\u00e4rkisid;<\/p>\n\n\n\n

\"See annab puhtalt retrospektiivseid enesehinnanguid isevalitud valimilt, kes ise ps\u00fchhedeelseid aineid manustavad... Sellise disaini puhul on oht saada kallutatud andmeid ja saadud tulemuste \u00fcldistatavus on vaid piiratud. See annab piiratud teavet selle kohta, millist rolli m\u00e4ngivad erinevad mehhanismid nende tajutud valuvaigistavate m\u00f5jude saavutamisel.\"<\/strong><\/em><\/p>\n\n\n\n

Autorid m\u00e4rkisid ka, et see t\u00e4hendab, et vaja on kontrollitud uuringuid. Selleks tuleb kavandada kliinilisi uuringuid, et uurimist\u00f6\u00f6d edasi viia. <\/p>\n\n\n\n

\"\"
Foto: Road Trip with Raj on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Mikrodoseerimise uurimisprogramm<\/h2>\n\n\n\n

Selle uuringu algatas tuntud ps\u00fchhedeelsete ainete propageerija Amanda Feilding, Beckley fondi asutaja ja direktor. See toimus p\u00e4rast seda, kui asutati\u00a0Beckley\/Maastrichti ps\u00fchhedeelsete uuringute programm<\/a>. P\u00f5nevaim, see programm on p\u00fchendatud m\u00f5ju uurimisele mikrodoseerimine<\/a> <\/strong>ps\u00fchhedeelikumide m\u00f5ju kognitiivsetele funktsioonidele, meeleolule ja valuhaldusele.\u00a0<\/p>\n\n\n\n

Varem oli programmi raames l\u00e4bi viidud platseebokontrollitud kliiniline uuring<\/a> 24 tervest vabatahtlikust. Selles uuringus leiti, et 20 mikrogrammi LSD annus v\u00f5ib v\u00f5rreldes platseeboga oluliselt v\u00e4hendada valu tajumistk\u00fclma pressori katse<\/a>'. Kui uuring avaldati 2020. aastal, \u00fctles Feilding;<\/p>\n\n\n\n

\"K\u00e4esolevad andmed n\u00e4itavad, et LSD v\u00e4ikesed annused v\u00f5ivad olla kasulikuks valuravi v\u00f5imaluseks, mis ei ole mitte ainult efektiivne patsientidel, vaid ka ilma problemaatiliste tagaj\u00e4rgedeta, mis on seotud praeguste p\u00f5hiravimitega, nagu opioidid...<\/strong><\/em>\"<\/p>\n\n\n\n

\"Need tulemused julgustavad mind, sest olen juba ammu uskunud, et LSD v\u00f5ib muuta mitte ainult valutunnet, vaid ka meie subjektiivset suhet sellega. Me peame j\u00e4tkama selle uurimist eesm\u00e4rgiga pakkuda ohutumaid, s\u00f5ltuvust mitte tekitavaid alternatiive valuravile ja tuua valuga inimesed sammu v\u00f5rra l\u00e4hemale \u00f5nnelikumale, tervislikumale ja t\u00e4ielikult v\u00e4ljendatud elule.\"<\/strong><\/em><\/p>\n\n\n\n

Hiljuti on l\u00f5petatud, ettevalmistamisel v\u00f5i veel k\u00e4imas arvukalt teisi valuvaigistamisega seotud uuringuid. MindMed uurib praegu ka LSD-d kroonilise valu puhul. Londoni Imperial College'i hiljutises uuringus leiti, et \u00fcheksa \u00fcheteistk\u00fcmnest kroonilise valu all kannatavast isikust teatasid t\u00e4ielikust v\u00f5i v\u00e4hemalt osalisest valuvaigistamisest. (v\u00f5i v\u00f5imetus valu tunda) <\/em>ps\u00fchhedeelikumidega eneseravi korral. <\/p>\n\n\n\n

Ps\u00fchhedeelse asja tugevdamine<\/h2>\n\n\n\n

Lisaks sellele kasutatakse ps\u00fchhedeelikute valu tekitavust ka selleks, et toetada nende kampaaniat legaliseerimise ja dekriminaliseerimise eest. N\u00e4iteks Californias ps\u00fchhedeelikute dekriminaliseerimise p\u00fc\u00fcdluses astus esile Joe Mackay, kes oli 9\/11 ajal esmaabiandja. Olles p\u00e4rast s\u00fcndmust kannatanud PTSD ja klastriliste peavalude all, otsustas ta p\u00e4rast pensionile j\u00e4\u00e4mist proovida end ravida maagiliste seente abil. Ps\u00fchhedeelsete ainete eestk\u00f5neleja kirjutas;<\/p>\n\n\n\n

\"Esimest korda paljude aastate jooksul tundsin ma oma tervise suhtes lootust. Ma l\u00f5petasin mulle m\u00e4\u00e4ratud tablettide kokteili v\u00f5tmise, millest paljud p\u00f5hjustasid kahjulikke k\u00f5rvalm\u00f5jusid ja tekitasid s\u00f5ltuvust... Psilots\u00fcbiin aitas mul ka taastada kontakti oma endise, r\u00f5\u00f5msameelse mina - Joe, keda mu s\u00f5brad ja perekond ei olnud n\u00e4inud p\u00e4rast 9\/11. Ei ole liialdus \u00f6elda, et psilots\u00fcbiin andis mulle mu elu tagasi. See on olnud transformatiivne ja v\u00f5imaldanud mul tunda \u00f5nne ja r\u00f5\u00f5mu nii, nagu ma kunagi arvasin, et ma seda enam ei saa.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"
Foto: freestocks on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Prioriteedi seadmine nii vaimse kui ka f\u00fc\u00fcsilise tervise osas<\/h2>\n\n\n\n

Vaimne tervis on sama oluline<\/a> nagu f\u00fc\u00fcsiline tervis; see m\u00f5iste on aga laiemas teadvuses suhteliselt uus. Ikka veel on neid, kes peavad f\u00fc\u00fcsilisi terviseh\u00e4dasid t\u00f5sisemaks v\u00f5i hooldamist v\u00e4\u00e4rivaks. \u00d5nneks, see on muutumas<\/strong>. V\u00f5ib-olla n\u00e4eme n\u00fc\u00fcd, et ps\u00fchhedeelsed ained osutuvad t\u00f5husaks nii f\u00fc\u00fcsilise valu kui ka vaimse tervise ravis, et nende propageerimine suureneb veelgi, mis toob kasu nii f\u00fc\u00fcsilisele kui ka vaimsele tervisele. Tundub, et ps\u00fchhedeelsed ained on kahekordne oht, mida me oleme oodanud<\/strong>...<\/p>","protected":false},"excerpt":{"rendered":"

A recent survey has found that chronic pain can be alleviated by microdoses of psilocybin, the psychoactive compound found in magic mushrooms.\u00a0 At this point you may be thinking \u2014 OK, so what\u00a0can\u2019t\u00a0psychedelics treat? And you\u2019d be forgiven for wondering. But as wild as it sounds, it\u2019s true. There\u00a0is\u00a0a growing area of research that shows […]<\/p>\n","protected":false},"author":11,"featured_media":10114,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-10110","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-and-studies"],"yoast_head":"\nStudy Finds Microdosing Psilocybin as Effective as Traditional Pain Medication<\/title>\n<meta name=\"description\" content=\"It's growing in popularity for mental health, but now a study finds microdosing psilocybin as effective as traditional paint medication!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.astrodose.eu\/et\/teadus-ja-uuringud\/uuring-leiab-et-psilotsubiini-mikrodoosimine-on-sama-tohus-kui-traditsioonilised-valuvaigistid\/\" \/>\n<meta property=\"og:locale\" content=\"et_EE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study Finds Microdosing Psilocybin as Effective as Traditional Pain Medication\" \/>\n<meta property=\"og:description\" content=\"It's growing in popularity for mental health, but now a study finds microdosing psilocybin as effective as traditional paint medication!\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.astrodose.eu\/et\/teadus-ja-uuringud\/uuring-leiab-et-psilotsubiini-mikrodoosimine-on-sama-tohus-kui-traditsioonilised-valuvaigistid\/\" \/>\n<meta property=\"og:site_name\" content=\"Astrodose - 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