{"id":10110,"date":"2024-05-07T15:40:59","date_gmt":"2024-05-07T13:40:59","guid":{"rendered":"https:\/\/www.astrodose.eu\/?p=10110"},"modified":"2024-05-07T15:40:59","modified_gmt":"2024-05-07T13:40:59","slug":"a-tanulmany-szerint-a-mikrodozisu-pszilocibin-ugyanolyan-hatekony-mint-a-hagyomanyos-fajdalomcsillapitas","status":"publish","type":"post","link":"https:\/\/www.astrodose.eu\/hu\/science-and-studies\/study-finds-microdosing-psilocybin-as-effective-as-traditional-pain-medication\/","title":{"rendered":"A tanulm\u00e1ny szerint a Psilocybin mikrod\u00f3zisa ugyanolyan hat\u00e9kony, mint a hagyom\u00e1nyos f\u00e1jdalomcsillap\u00edt\u00e1s"},"content":{"rendered":"

Egy nemr\u00e9giben k\u00e9sz\u00fclt felm\u00e9r\u00e9s szerint a kr\u00f3nikus f\u00e1jdalmat enyh\u00edtheti a var\u00e1zsgomb\u00e1ban tal\u00e1lhat\u00f3 pszichoakt\u00edv vegy\u00fclet, a pszilocibin mikrod\u00f3zisa.\u00a0<\/strong><\/p>\n\n\n\n

Ezen a ponton lehet, hogy azt gondolja - OK, sz\u00f3val mi\u00a0nem lehet\u00a0<\/em>pszichedelikus szerekkel kezel? \u00c9s megbocs\u00e1that\u00f3, ha elgondolkodik. De b\u00e1rmennyire is vadul hangzik, ez igaz. A\u00a0a<\/em>\u00a0a kutat\u00e1sok egyre n\u00f6vekv\u0151 ter\u00fclete, amely azt mutatja.<\/strong> ezek a kor\u00e1bban bizalmatlan anyagok balzsamot jelenthetnek a fizikai f\u00e1jdalmakra, r\u00e1ad\u00e1sul a nagyobb nyilv\u00e1noss\u00e1got kapott szerep\u00fck\u00f6n t\u00fal, mint a pszichol\u00f3giai k\u00e9rd\u00e9sek<\/a>.\u00a0<\/strong><\/p>\n\n\n\n

A pszichedelikus szerek hat\u00e9konyabbak, mint a hagyom\u00e1nyos gy\u00f3gyszerek<\/h2>\n\n\n\n

A\u00a0tanulm\u00e1ny<\/a>, megjelent 2023 augusztus\u00e1ban, (a t\u00fals\u00e1gosan tal\u00e1l\u00f3an elnevezett European Journal of Pain c\u00edm\u0171 foly\u00f3iratban)\u00a0<\/em>meg\u00e1llap\u00edtott\u00e1k, hogy a klasszikus pszichedelikus szerek d\u00f3zisai - mint p\u00e9ld\u00e1ul a\u00a0pszilocibin,<\/strong>\u00a0LSD<\/strong>,\u00a0meszkalin<\/strong>\u00a0\u00e9s\u00a0DMT<\/strong>\u00a0- hat\u00e9konyak voltak a kr\u00f3nikus f\u00e1jdalom kezel\u00e9s\u00e9ben. Mind a makro-, mind a\u00a0mikrod\u00f3zisok<\/strong>\u00a0ezek az anyagok a k\u00f6vetkez\u0151kh\u00f6z vezettek\u00a0jobb f\u00e1jdalomcsillap\u00edt\u00e1s<\/strong>\u00a0a hagyom\u00e1nyos gy\u00f3gyszerekhez k\u00e9pest<\/strong>. A felm\u00e9r\u00e9sben 170 \u00f6nk\u00e9ntes vett r\u00e9szt.\u00a0<\/p>\n\n\n\n

A lap \u00f6sszegezte az eredm\u00e9nyeket;<\/p>\n\n\n\n

\"A r\u00e9sztvev\u0151k arr\u00f3l sz\u00e1moltak be, hogy a teljes d\u00f3zisok l\u00e1that\u00f3an jobb \u00e9rz\u00e9kelhet\u0151 eredm\u00e9nyeket \u00e9rnek el a f\u00e1jdalomcsillap\u00edt\u00e1sban, mint a mikrod\u00f3zisok, m\u00edg a mikrod\u00f3zisok hat\u00e9konys\u00e1ga a felm\u00e9r\u00e9sben r\u00e9sztvev\u0151k szerint a hagyom\u00e1nyos gy\u00f3gyszerek\u00e9hez hasonl\u00f3nak t\u0171nik.\".<\/strong><\/em><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

F\u00e1jdalomcsillap\u00edt\u00e1s ak\u00e1r 3 napig vagy tov\u00e1bb<\/h4>\n\n\n\n

A tanulm\u00e1nyban a kutat\u00f3k \u00f6t k\u00f6r\u00fclm\u00e9nyre \u00f6sszpontos\u00edtottak. Ezek az \u00edz\u00fcleti gyullad\u00e1s, a migr\u00e9n, fibromyalgia<\/a>, fesz\u00fclts\u00e9gt\u00edpus\u00fa fejf\u00e1j\u00e1s \u00e9s isi\u00e1sz<\/a>. <\/p>\n\n\n\n

A felm\u00e9r\u00e9sben az isi\u00e1sz kiv\u00e9tel\u00e9vel az \u00f6sszes t\u00f6bbi betegs\u00e9get (\u00edgy 4 az 5-b\u0151l<\/strong>) <\/em>a besz\u00e1mol\u00f3k szerint a pszichedelikus szerek enyh\u00edtett\u00e9k. Ez volt a leghat\u00e9konyabb az adagol\u00e1s napj\u00e1n<\/strong>, b\u00e1r az is 1 \u00e9s 3 nap k\u00f6z\u00f6tt <\/strong>k\u00e9s\u0151bb. N\u00e9h\u00e1ny megk\u00e9rdezett m\u00e9g f\u00e1jdalomcsillap\u00edt\u00e1sr\u00f3l is besz\u00e1molt a harmadik napon t\u00fal. <\/strong><\/p>\n\n\n\n

Psilocybin<\/strong> \u00e9s LSD<\/strong> voltak a felm\u00e9r\u00e9sben r\u00e9sztvev\u0151k \u00e1ltal leggyakrabban haszn\u00e1lt gy\u00f3gyszerek. <\/p>\n\n\n\n

A k\u00e9rd\u00e9s, hogy mi\u00e9rt <\/em>pszichedelikus szerek nem voltak hat\u00e9konyak, vagy legal\u00e1bbis \"statisztikailag nem szignifik\u00e1ns\" <\/em>az isi\u00e1szon is elgondolkodtak a kutat\u00f3k. Azt \u00edrt\u00e1k;<\/p>\n\n\n\n

 \"Ez az eredm\u00e9ny azt jelezheti, hogy ezek az anyagok csak bizonyos t\u00edpus\u00fa f\u00e1jdalom\u00e1llapotok eset\u00e9ben \u00edg\u00e9retesek, feltehet\u0151en azokn\u00e1l, amelyekben a gyullad\u00e1sos \u00e9s\/vagy pszichoszomatikus komponensek jelent\u0151sebb szerepet j\u00e1tszanak.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"
Fot\u00f3: CHUTTERSNAP on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

A kr\u00f3nikus f\u00e1jdalom vil\u00e1gszerte hatalmas probl\u00e9ma<\/h2>\n\n\n\n

Ez t\u00fckr\u00f6zi\u00a0kor\u00e1bbi kutat\u00e1sok<\/a>\u00a0\u00e9s spekul\u00e1ci\u00f3kat, hogy a pszichedelikus szerek hat\u00e1sos\u00a0gyullad\u00e1scs\u00f6kkent\u0151<\/strong>. Val\u00f3j\u00e1ban ez a tanulm\u00e1ny visszhangozza a pszichedelikus szerek kr\u00f3nikus f\u00e1jdalomra gyakorolt hat\u00e1s\u00e1t vizsg\u00e1l\u00f3 kutat\u00f3k kor\u00e1bbi eredm\u00e9nyeit - a\u00a0nagyon \u00edg\u00e9retes jel<\/strong>! Egy hatalmas\u00a020% a vil\u00e1g n\u00e9pess\u00e9g\u00e9nek<\/strong>\u00a0szenvednek\u00a0kr\u00f3nikus f\u00e1jdalom\u00a0<\/strong>valamilyen form\u00e1ban. Forradalmi jelent\u0151s\u00e9g\u0171 lehet, ha \u00faj m\u00f3dszereket tal\u00e1lunk ennek a probl\u00e9m\u00e1nak a kezel\u00e9s\u00e9re. A szerz\u0151k azonban elismert\u00e9k a tanulm\u00e1ny n\u00e9h\u00e1ny korl\u00e1tj\u00e1t. A legnagyobb a vizsg\u00e1lat fel\u00e9p\u00edt\u00e9s\u00e9ben rejlett. A kutat\u00f3k megjegyezt\u00e9k;<\/p>\n\n\n\n

\"Tiszt\u00e1n retrospekt\u00edv \u00f6n\u00e9rt\u00e9kel\u00e9seket ny\u00fajt a pszichedelikus szereket \u00f6nmagukban alkalmaz\u00f3 egy\u00e9nek \u00f6nmaga \u00e1ltal kiv\u00e1lasztott mint\u00e1j\u00e1b\u00f3l... Ez a tervezet mag\u00e1ban hordozza az elfogult adatok megszerz\u00e9s\u00e9nek kock\u00e1zat\u00e1t, \u00e9s az el\u0151\u00e1ll\u00edtott eredm\u00e9nyek \u00e1ltal\u00e1nos\u00edthat\u00f3s\u00e1ga csak korl\u00e1tozott. Korl\u00e1tozott inform\u00e1ci\u00f3t ny\u00fajt annak a szerepnek a sz\u00e9tv\u00e1laszt\u00e1s\u00e1hoz, amelyet a k\u00fcl\u00f6nb\u00f6z\u0151 mechanizmusok j\u00e1tszanak az \u00e9szlelt f\u00e1jdalomcsillap\u00edt\u00f3 hat\u00e1sok el\u00e9r\u00e9s\u00e9ben.\"<\/strong><\/em><\/p>\n\n\n\n

A szerz\u0151k azt is megjegyezt\u00e9k, hogy ez azt jelenti, hogy ellen\u0151rz\u00f6tt vizsg\u00e1latokra van sz\u00fcks\u00e9g. Ehhez klinikai vizsg\u00e1latokat kell tervezni, hogy a kutat\u00e1st tov\u00e1bb lehessen vinni. <\/p>\n\n\n\n

\"\"
Fot\u00f3: Road Trip with Raj on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Mikroadagol\u00e1si kutat\u00e1si program<\/h2>\n\n\n\n

A felm\u00e9r\u00e9st Amanda Feilding, a Beckley Alap\u00edtv\u00e1ny alap\u00edt\u00f3ja \u00e9s igazgat\u00f3ja, a pszichedelikus szerek ismert sz\u00f3sz\u00f3l\u00f3ja kezdem\u00e9nyezte. Azut\u00e1n j\u00f6tt l\u00e9tre, hogy a\u00a0A Beckley\/Maastrichti Pszichedelikus Kutat\u00e1si Program<\/a>. Izgalmas, hogy ez a program szentelt tanulm\u00e1nyozza a hat\u00e1sait mikroadagol\u00e1s<\/a> <\/strong>pszichedelikus szerek hat\u00e1sa a kognit\u00edv funkci\u00f3kra, a hangulatra \u00e9s a f\u00e1jdalomcsillap\u00edt\u00e1sra.\u00a0<\/p>\n\n\n\n

Kor\u00e1bban a program egy placebo-kontroll\u00e1lt klinikai tanulm\u00e1ny<\/a> 24 eg\u00e9szs\u00e9ges \u00f6nk\u00e9ntes. Ebben a vizsg\u00e1latban azt tal\u00e1lt\u00e1k, hogy 20 mikrogramm LSD d\u00f3zis jelent\u0151sen cs\u00f6kkentette a f\u00e1jdalom\u00e9rzetet a placeb\u00f3hoz k\u00e9pest egyhidegnyom\u00e1sos teszt<\/a>'. Amikor a tanulm\u00e1nyt 2020-ban k\u00f6zz\u00e9tett\u00e9k, Feilding azt mondta;<\/p>\n\n\n\n

\"A jelen adatok azt sugallj\u00e1k, hogy az LSD alacsony d\u00f3zisai hasznos f\u00e1jdalomcsillap\u00edt\u00e1si lehet\u0151s\u00e9get jelenthetnek, amely nem csak hat\u00e9kony a betegekn\u00e9l, de mentes a jelenlegi f\u0151 gy\u00f3gyszerek, p\u00e9ld\u00e1ul az opioidok probl\u00e9m\u00e1s k\u00f6vetkezm\u00e9nyeit\u0151l is....<\/strong><\/em>\"<\/p>\n\n\n\n

\"Ezek az eredm\u00e9nyek b\u00e1tor\u00edtanak, mivel r\u00e9g\u00f3ta hiszem, hogy az LSD nemcsak a f\u00e1jdalom\u00e9rzetet, hanem a hozz\u00e1 val\u00f3 szubjekt\u00edv viszonyunkat is megv\u00e1ltoztathatja. Ezt tov\u00e1bb kell kutatnunk azzal a c\u00e9llal, hogy biztons\u00e1gosabb, f\u00fcgg\u0151s\u00e9get nem okoz\u00f3 alternat\u00edv\u00e1kat k\u00edn\u00e1ljunk a f\u00e1jdalomcsillap\u00edt\u00e1sra, \u00e9s hogy a f\u00e1jdalomt\u00f3l szenved\u0151 embereket egy l\u00e9p\u00e9ssel k\u00f6zelebb hozzuk ahhoz, hogy boldogabb, eg\u00e9szs\u00e9gesebb \u00e9s teljesebben kifejezett \u00e9letet \u00e9ljenek.\"<\/strong><\/em><\/p>\n\n\n\n

Sz\u00e1mos m\u00e1s, a f\u00e1jdalomcsillap\u00edt\u00e1ssal kapcsolatos vizsg\u00e1latot nemr\u00e9giben fejeztek be, \u00e1llnak sorban, vagy m\u00e9g folyamatban vannak. A MindMed jelenleg is vizsg\u00e1lja az LSD kr\u00f3nikus f\u00e1jdalmakra val\u00f3 alkalmaz\u00e1s\u00e1t. A londoni Imperial College nemr\u00e9giben v\u00e9gzett tanulm\u00e1nya szerint tizenegy kr\u00f3nikus f\u00e1jdalomt\u00f3l szenved\u0151 betegb\u0151l kilenc teljes vagy legal\u00e1bb r\u00e9szleges f\u00e1jdalomcsillap\u00edt\u00e1sr\u00f3l sz\u00e1molt be. (vagy f\u00e1jdalom\u00e9rz\u00e9sre val\u00f3 k\u00e9ptelens\u00e9g) <\/em>amikor pszichedelikus szerekkel kezelik magukat. <\/p>\n\n\n\n

A pszichedelikus \u00fcgy meger\u0151s\u00edt\u00e9se<\/h2>\n\n\n\n

Emellett a pszichedelikus szerek f\u00e1jdalomcsillap\u00edt\u00f3 potenci\u00e1lj\u00e1t is felhaszn\u00e1lj\u00e1k a legaliz\u00e1l\u00e1s\u00e9rt \u00e9s a dekriminaliz\u00e1l\u00e1s\u00e9rt folytatott kamp\u00e1nyuk t\u00e1mogat\u00e1s\u00e1ra. A pszichedelikus szerek dekriminaliz\u00e1l\u00e1s\u00e1ra ir\u00e1nyul\u00f3 kaliforniai k\u00eds\u00e9rletben p\u00e9ld\u00e1ul Joe Mackay, aki 9\/11 idej\u00e9n els\u0151seg\u00e9lyny\u00fajt\u00f3 volt, jelentkezett. Mivel az esem\u00e9ny \u00f3ta poszttraum\u00e1s stressz-szindr\u00f3m\u00e1ban \u00e9s cluster fejf\u00e1j\u00e1sban szenvedett, nyugd\u00edjaz\u00e1sa ut\u00e1n \u00fagy d\u00f6nt\u00f6tt, hogy var\u00e1zsgomb\u00e1k seg\u00edts\u00e9g\u00e9vel pr\u00f3b\u00e1lja meggy\u00f3gy\u00edtani mag\u00e1t. A pszichedelikumok \u00fcgy\u00e9nek sz\u00f3sz\u00f3l\u00f3jak\u00e9nt azt \u00edrta;<\/p>\n\n\n\n

\"Hossz\u00fa \u00e9vek \u00f3ta el\u0151sz\u00f6r \u00e9reztem rem\u00e9nyt az eg\u00e9szs\u00e9gemet illet\u0151en. Abbahagytam a fel\u00edrt tablettakokt\u00e9lok szed\u00e9s\u00e9t, amelyek k\u00f6z\u00fcl sok k\u00e1ros mell\u00e9khat\u00e1sokat okozott \u00e9s f\u00fcgg\u0151s\u00e9get okozott... A pszilocibin seg\u00edtett abban is, hogy \u00fajra kapcsolatba ker\u00fcljek kor\u00e1bbi, boldog-boldogtalan \u00e9nemmel - azzal a Joe-val, akit a bar\u00e1taim \u00e9s a csal\u00e1dom 9\/11 \u00f3ta nem l\u00e1ttak. Nem t\u00falz\u00e1s azt mondani, hogy a pszilocibin visszaadta az \u00e9letemet. \u00c1talak\u00edt\u00f3 hat\u00e1ssal volt r\u00e1m, \u00e9s lehet\u0151v\u00e9 tette, hogy olyan m\u00f3don \u00e9rezzem a boldogs\u00e1got \u00e9s az \u00f6r\u00f6m\u00f6t, ahogyan soha t\u00f6bb\u00e9 nem gondoltam volna.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"
Fot\u00f3: freestocks on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

A ment\u00e1lis \u00e9s a fizikai eg\u00e9szs\u00e9g priorit\u00e1sk\u00e9nt val\u00f3 kezel\u00e9se<\/h2>\n\n\n\n

A ment\u00e1lis eg\u00e9szs\u00e9g ugyanolyan fontos<\/a> mint a fizikai eg\u00e9szs\u00e9g; ez a fogalom azonban viszonylag \u00faj a sz\u00e9lesebb tudatban. M\u00e9g mindig vannak olyanok, akik a fizikai betegs\u00e9geket s\u00falyosabbnak vagy ell\u00e1t\u00e1sra \u00e9rdemesnek tartj\u00e1k. Szerencs\u00e9re, ez v\u00e1ltozik<\/strong>. Tal\u00e1n most, hogy a pszichedelikus szerek a fizikai f\u00e1jdalom \u00e9s a ment\u00e1lis eg\u00e9szs\u00e9g kezel\u00e9s\u00e9ben is hat\u00e9konynak bizonyulnak, m\u00e9g nagyobb m\u00e9rt\u00e9kben fogjuk t\u00e1mogatni a fizikai \u00e9s ment\u00e1lis eg\u00e9szs\u00e9gi okok jav\u00e1t egyar\u00e1nt. \u00dagy t\u0171nik, hogy a pszichedelikus szerek a kett\u0151s fenyeget\u00e9s, amire v\u00e1rtunk<\/strong>...<\/p>","protected":false},"excerpt":{"rendered":"

A recent survey has found that chronic pain can be alleviated by microdoses of psilocybin, the psychoactive compound found in magic mushrooms.\u00a0 At this point you may be thinking \u2014 OK, so what\u00a0can\u2019t\u00a0psychedelics treat? And you\u2019d be forgiven for wondering. But as wild as it sounds, it\u2019s true. There\u00a0is\u00a0a growing area of research that shows […]<\/p>\n","protected":false},"author":11,"featured_media":10114,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-10110","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-and-studies"],"yoast_head":"\nStudy Finds Microdosing Psilocybin as Effective as Traditional Pain Medication<\/title>\n<meta name=\"description\" content=\"It's growing in popularity for mental health, but now a study finds microdosing psilocybin as effective as traditional paint medication!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.astrodose.eu\/hu\/tudomany-es-tanulmanyok\/a-tanulmany-szerint-a-mikrodozisu-pszilocibin-ugyanolyan-hatekony-mint-a-hagyomanyos-fajdalomcsillapitas\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study Finds Microdosing Psilocybin as Effective as Traditional Pain Medication\" \/>\n<meta property=\"og:description\" content=\"It's growing in popularity for mental health, but now a study finds microdosing psilocybin as effective as traditional paint medication!\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.astrodose.eu\/hu\/tudomany-es-tanulmanyok\/a-tanulmany-szerint-a-mikrodozisu-pszilocibin-ugyanolyan-hatekony-mint-a-hagyomanyos-fajdalomcsillapitas\/\" \/>\n<meta property=\"og:site_name\" content=\"Astrodose - 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