{"id":10110,"date":"2024-05-07T15:40:59","date_gmt":"2024-05-07T13:40:59","guid":{"rendered":"https:\/\/www.astrodose.eu\/?p=10110"},"modified":"2024-05-07T15:40:59","modified_gmt":"2024-05-07T13:40:59","slug":"studie-finner-mikrodosering-psilocybin-lika-effektiv-som-traditionell-smartstillande-medicin","status":"publish","type":"post","link":"https:\/\/www.astrodose.eu\/sv\/science-and-studies\/study-finds-microdosing-psilocybin-as-effective-as-traditional-pain-medication\/","title":{"rendered":"Studie finner mikrodosering Psilocybin lika effektiv som traditionell sm\u00e4rtstillande medicinering"},"content":{"rendered":"

En nyligen genomf\u00f6rd unders\u00f6kning har visat att kronisk sm\u00e4rta kan lindras av mikrodoser av psilocybin, den psykoaktiva f\u00f6rening som finns i magiska svampar.\u00a0<\/strong><\/p>\n\n\n\n

Vid denna tidpunkt kanske du t\u00e4nker - OK, s\u00e5 vad\u00a0kan inte\u00a0<\/em>psykedelika behandla? Och du skulle bli f\u00f6rl\u00e5ten f\u00f6r att undra. Men s\u00e5 vilt som det l\u00e5ter, \u00e4r det sant. D\u00e4r\u00a0\u00e4r<\/em>\u00a0ett v\u00e4xande forskningsomr\u00e5de som visar<\/strong> dessa tidigare misstrodda substanser kan vara ett balsam f\u00f6r fysisk sm\u00e4rta, ut\u00f6ver deras mer omtalade roll som behandling f\u00f6r psykologiska fr\u00e5gor<\/a>.\u00a0<\/strong><\/p>\n\n\n\n

Psykedelika mer effektiva \u00e4n konventionella mediciner<\/h2>\n\n\n\n

The\u00a0studera<\/a>, publicerad i augusti 2023, (i European Journal of Pain med det alltf\u00f6r passande namnet)\u00a0<\/em>fann att doser av klassiska psykedelika - s\u00e5som\u00a0psilocybin,<\/strong>\u00a0LSD<\/strong>,\u00a0meskalin<\/strong>\u00a0och\u00a0DMT<\/strong>\u00a0- var effektiva vid behandling av kronisk sm\u00e4rta. I b\u00e5de makro- och\u00a0mikrodoser<\/strong>\u00a0dessa \u00e4mnen visade sig leda till\u00a0b\u00e4ttre sm\u00e4rtlindring<\/strong>\u00a0j\u00e4mf\u00f6rt med konventionella mediciner<\/strong>. Unders\u00f6kningen bestod av 170 frivilliga.\u00a0<\/p>\n\n\n\n

I tidningen sammanfattades resultaten;<\/p>\n\n\n\n

\"Deltagarna rapporterade att fulla doser verkar ge b\u00e4ttre upplevda resultat n\u00e4r det g\u00e4ller sm\u00e4rtlindring \u00e4n mikrodosering, medan mikrodoseringens effektivitet verkar j\u00e4mf\u00f6rbar med den f\u00f6r konventionell medicinering enligt deltagarna i unders\u00f6kningen.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Sm\u00e4rtlindring i upp till 3 dagar eller mer<\/h4>\n\n\n\n

I studien fokuserade forskarna p\u00e5 fem tillst\u00e5nd. Dessa var artrit, migr\u00e4n, fibromyalgi<\/a>, huvudv\u00e4rk av sp\u00e4nningstyp och ischias<\/a>. <\/p>\n\n\n\n

I unders\u00f6kningen visade det sig att med undantag f\u00f6r ischias var alla de andra tillst\u00e5nden (s\u00e5 4 utav 5<\/strong>) <\/em>rapporterades bli lindrade av psykedelika. Detta var mest effektiv p\u00e5 doseringsdagen<\/strong>men ocks\u00e5 mellan 1 och 3 dagar <\/strong>senare. Ett f\u00e5tal av de tillfr\u00e5gade rapporterade till och med sm\u00e4rtlindring efter den tredje dagen. <\/strong><\/p>\n\n\n\n

Psilocybin<\/strong> och LSD<\/strong> var de vanligaste drogerna som deltagarna i unders\u00f6kningen anv\u00e4nde. <\/p>\n\n\n\n

Fr\u00e5gan om varf\u00f6r <\/em>psykedelika var icke-effektiva, eller \u00e5tminstone \"statistiskt icke-signifikant\" <\/em>p\u00e5 ischias \u00f6verv\u00e4gdes ocks\u00e5 av forskarna. De skrev;<\/p>\n\n\n\n

 \"Detta resultat kan tyda p\u00e5 att dessa substanser endast \u00e4r lovande f\u00f6r vissa typer av sm\u00e4rttillst\u00e5nd, f\u00f6rmodligen s\u00e5dana d\u00e4r inflammatoriska och\/eller psykosomatiska komponenter spelar en mer framtr\u00e4dande roll.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"
Foto av CHUTTERSNAP p\u00e5 Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Kronisk sm\u00e4rta \u00e4r ett stort problem globalt<\/h2>\n\n\n\n

Detta \u00e5terspeglar\u00a0tidigare forskning<\/a>\u00a0och spekulationer om att psykedelika kan fungera som effektiva\u00a0antiinflammatorisk<\/strong>. I sj\u00e4lva verket ekar denna studie tidigare resultat fr\u00e5n forskare som studerar effekterna av psykedelika p\u00e5 kronisk sm\u00e4rta - a\u00a0mycket lovande tecken<\/strong>! En hel del\u00a020% av v\u00e4rldens befolkning<\/strong>\u00a0lida av\u00a0kronisk sm\u00e4rta\u00a0<\/strong>av n\u00e5got slag. Att hitta nya s\u00e4tt att potentiellt behandla denna fr\u00e5ga skulle kunna vara revolutionerande. F\u00f6rfattarna erk\u00e4nde dock vissa begr\u00e4nsningar i studien. Den st\u00f6rsta var i utformningen av sj\u00e4lva studien. Forskarna noterade;<\/p>\n\n\n\n

\"Det ger rent retrospektiva sj\u00e4lvbed\u00f6mningar fr\u00e5n ett sj\u00e4lvvalt urval av individer som sj\u00e4lvadministrerar psykedelika ... Denna design medf\u00f6r risken f\u00f6r att f\u00e5 partiska data och generaliserbarheten av de producerade resultaten \u00e4r endast begr\u00e4nsad. Den ger begr\u00e4nsad information f\u00f6r att reda ut den roll som olika mekanismer spelar f\u00f6r att uppn\u00e5 dessa upplevda sm\u00e4rtstillande effekter.\"<\/strong><\/em><\/p>\n\n\n\n

F\u00f6rfattarna noterade ocks\u00e5 att detta inneb\u00e4r att det beh\u00f6vs kontrollerade studier. F\u00f6r detta m\u00e5ste kliniska pr\u00f6vningar utformas f\u00f6r att driva forskningen vidare. <\/p>\n\n\n\n

\"\"
Foto av Road Trip med Raj p\u00e5 Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Forskningsprogram f\u00f6r mikrodosering<\/h2>\n\n\n\n

Denna unders\u00f6kning hade initierats av den v\u00e4lk\u00e4nda psykedeliska f\u00f6respr\u00e5karen Amanda Feilding, grundare och chef f\u00f6r Beckley Foundation. Det kom efter uppr\u00e4ttandet av\u00a0Det psykedeliska forskningsprogrammet Beckley\/Maastricht<\/a>. Sp\u00e4nnande nog \u00e4r detta program inriktat p\u00e5 att studera effekterna av Mikrodosering<\/a> <\/strong>psykedelika p\u00e5 kognitiva funktioner, hum\u00f6r och sm\u00e4rtlindring.\u00a0<\/p>\n\n\n\n

Tidigare hade programmet genomf\u00f6rt en placebokontrollerad klinisk studera<\/a> p\u00e5 24 friska frivilliga f\u00f6rs\u00f6kspersoner. I denna studie fann man att en dos p\u00e5 20 mikrogram LSD signifikant kunde minska sm\u00e4rtupplevelsen, j\u00e4mf\u00f6rt med placebo, under enkallt tryckprov<\/a>'. N\u00e4r studien publicerades, \u00e5r 2020, sa Feilding;<\/p>\n\n\n\n

\"De aktuella uppgifterna tyder p\u00e5 att l\u00e5ga doser LSD kan utg\u00f6ra ett anv\u00e4ndbart behandlingsalternativ f\u00f6r sm\u00e4rtlindring som inte bara \u00e4r effektivt hos patienter utan ocks\u00e5 saknar de problematiska konsekvenser som \u00e4r f\u00f6rknippade med nuvarande huvudl\u00e4kemedel, s\u00e5som opioider ...<\/strong><\/em>\"<\/p>\n\n\n\n

\"Jag \u00e4r uppmuntrad av dessa resultat eftersom jag l\u00e4nge har trott att LSD inte bara kan f\u00f6r\u00e4ndra sm\u00e4rtupplevelserna utan ocks\u00e5 v\u00e5r subjektiva relation till dem. Vi m\u00e5ste forts\u00e4tta att utforska detta i syfte att tillhandah\u00e5lla s\u00e4krare, icke beroendeframkallande alternativ till sm\u00e4rtlindring och f\u00f6r att f\u00f6ra m\u00e4nniskor med sm\u00e4rta ett steg n\u00e4rmare ett lyckligare, h\u00e4lsosammare och fullt uttryckt liv.\"<\/strong><\/em><\/p>\n\n\n\n

Det finns m\u00e5nga andra sm\u00e4rtlindringsrelaterade studier som nyligen avslutats, p\u00e5b\u00f6rjats eller fortfarande p\u00e5g\u00e5r. MindMed unders\u00f6ker ocks\u00e5 f\u00f6r n\u00e4rvarande LSD f\u00f6r kronisk sm\u00e4rta. En nyligen genomf\u00f6rd studie vid Imperial College London visade att nio av elva kroniska sm\u00e4rtpatienter rapporterade total eller \u00e5tminstone partiell analgesi (eller of\u00f6rm\u00e5ga att k\u00e4nna sm\u00e4rta) <\/em>n\u00e4r man sj\u00e4lvmedicinerar med psykedelika. <\/p>\n\n\n\n

F\u00f6rst\u00e4rkning av den psykedeliska saken<\/h2>\n\n\n\n

Dessutom anv\u00e4nds psykedelikernas sm\u00e4rtlindrande potential ocks\u00e5 f\u00f6r att st\u00e4rka deras kampanj f\u00f6r legalisering och avkriminalisering. Till exempel, i Kaliforniens f\u00f6rs\u00f6k att avkriminalisera psykedelika, kom Joe Mackay, som hade varit en f\u00f6rsta svarare under 9\/11, fram. Efter att ha lidit av PTSD och klusterhuvudv\u00e4rk sedan h\u00e4ndelsen, n\u00e4r han gick i pension best\u00e4mde han sig f\u00f6r att f\u00f6rs\u00f6ka l\u00e4ka sig sj\u00e4lv med magiska svampar. En f\u00f6respr\u00e5kare f\u00f6r den psykedeliska orsaken, skrev han;<\/p>\n\n\n\n

\"F\u00f6r f\u00f6rsta g\u00e5ngen p\u00e5 m\u00e5nga \u00e5r k\u00e4nde jag mig hoppfull om min h\u00e4lsa. Jag slutade ta den cocktail av piller som jag hade ordinerats, varav m\u00e5nga orsakade skadliga biverkningar och var beroendeframkallande ... Psilocybin hj\u00e4lpte mig ocks\u00e5 att komma tillbaka i kontakt med mitt tidigare, glada och lyckliga jag - den Joe som mina v\u00e4nner och familj inte hade sett sedan 9\/11. Det \u00e4r ingen \u00f6verdrift att s\u00e4ga att psilocybin gav mig mitt liv tillbaka. Det har varit omv\u00e4lvande och gjort det m\u00f6jligt f\u00f6r mig att k\u00e4nna lycka och gl\u00e4dje p\u00e5 ett s\u00e4tt som jag aldrig trodde att jag skulle g\u00f6ra igen.\"<\/strong><\/em><\/p>\n\n\n\n

\"\"
Foto av freestocks p\u00e5 Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Prioritera b\u00e5de psykisk och fysisk h\u00e4lsa<\/h2>\n\n\n\n

Psykisk h\u00e4lsa \u00e4r lika viktigt<\/a> som fysisk h\u00e4lsa; detta begrepp \u00e4r dock relativt nytt i det allm\u00e4nna medvetandet. Det finns fortfarande de som anser att fysiska \u00e5kommor \u00e4r allvarligare eller mer v\u00e4rda att ta hand om. Lyckligtvis \u00e4r det s\u00e5, detta h\u00e5ller p\u00e5 att f\u00f6r\u00e4ndras<\/strong>. Kanske nu n\u00e4r psykedelika visar sig vara effektiva vid behandling av fysisk sm\u00e4rta s\u00e5v\u00e4l som mental h\u00e4lsa kommer vi att se en \u00e4nnu st\u00f6rre \u00f6kning av f\u00f6respr\u00e5kandet, vilket gynnar b\u00e5de fysiska och psykiska h\u00e4lsofr\u00e5gor. Psykedelika, verkar det, \u00e4r dubbelt hot som vi har v\u00e4ntat p\u00e5<\/strong>...<\/p>","protected":false},"excerpt":{"rendered":"

A recent survey has found that chronic pain can be alleviated by microdoses of psilocybin, the psychoactive compound found in magic mushrooms.\u00a0 At this point you may be thinking \u2014 OK, so what\u00a0can\u2019t\u00a0psychedelics treat? And you\u2019d be forgiven for wondering. But as wild as it sounds, it\u2019s true. There\u00a0is\u00a0a growing area of research that shows […]<\/p>\n","protected":false},"author":11,"featured_media":10114,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-10110","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-and-studies"],"yoast_head":"\nStudy Finds Microdosing Psilocybin as Effective as Traditional Pain Medication<\/title>\n<meta name=\"description\" content=\"It's growing in popularity for mental health, but now a study finds microdosing psilocybin as effective as traditional paint medication!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.astrodose.eu\/sv\/vetenskap-och-studier\/studie-finner-mikrodosering-psilocybin-lika-effektiv-som-traditionell-smartstillande-medicin\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study Finds Microdosing Psilocybin as Effective as Traditional Pain Medication\" \/>\n<meta property=\"og:description\" content=\"It's growing in popularity for mental health, but now a study finds microdosing psilocybin as effective as traditional paint medication!\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.astrodose.eu\/sv\/vetenskap-och-studier\/studie-finner-mikrodosering-psilocybin-lika-effektiv-som-traditionell-smartstillande-medicin\/\" \/>\n<meta property=\"og:site_name\" content=\"Astrodose - 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